Interfaces are subject to 80/20 principle and distribution of interaction as much as anything else is.
If you are designing a screen, bare in mind the likelihood that top left area of the screen will be looked at the most by most people.
It should contain the most important information that the user is looking for.
It will cover anywhere up to 50% of information needs if not more.
The rest of the areas will be less and less looked at.
So your prioritisation of the information ought to work according to these principles.
Here is a 30 second sketch of a template that governs the macro structure of the screen.
Going from macro down to micro detail is the best way to design with solid meaning to it and achieve high level of relevance and quality.